Pharma Quiz 80


They’re all antibacterials belonging to the class of quinolones, except for nalidixic acid which technically is a naphthyridine. The structures are all in order from 1st generation to the fourth generation. Nalidixic acid is the prototype of this class of antibacterials and it’s not the structure of the image. Ciprofloxacin has an N- substituent that is a CYcloPROpyl, so it matches the structure in the image. Levofloxacin is a third-generation quinolone that is active against streptococci. Moxifloxacin also has an N-cyclopropyl, but it also has a 2,8-diazabicyclo[4.3.0]nonan-8-yl] moiety. It is a fourth-generation quinolone that shows less development of resistance.

The correct answer is B.


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