Lactic acidosis, reduced absorption of vitamin B12, stomach upset, bloating, flatulence, and unpleasant metallic taste are all side effects of the active ingredient Metformin (brand name Glucophage® among many others), a biguanide medication used as a drug of choice in the treatment of type 2 diabetes. Metformin-induced lactic acidosis (MALA) is a condition where the concentration of lactate increases in the plasma due to preexisting conditions like renal impairment that increases metformin levels. Symptoms of lactic acidosis include abdominal pain, tiredness, diarrhea, loss of appetite, and general discomfort.
The correct answer is D.
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