Pharma Quiz 96



Vitamin K is the antidote to the blood thinner Warfarin (best known under the brand name Coumadin®), a vitamin K antagonist that is used to prevent the formation of blood clots. It works by inhibiting the formation of clotting factors II, VII, IX, and X which is a vitamin K-dependent biosynthesis. Warfarin is used in the treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE). The main side effect of Warfarin overdose (which can happen due to interaction with many medications) is bleeding, and it can be reversed by administration of Vitamin K, prothrombin complex concentrate, and fresh frozen plasma.

The correct answer is C.

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