Pharma Quiz 71



L-DOPA is an amino acid used in the treatment of Parkinson’s disease. One cannot just administer dopamine because the blood-brain barrier is impermeable to it. Aminoacids instead can be absorbed by specific carriers. Melevodopa is the methyl ester of L-DOPA, it is a prodrug with a higher solubility than the actual active form. Carbidopa is a dopa decarboxylase inhibitor used in association with L-DOPA to prevent the peripheric decarboxylation of L-DOPA. The drug of choice used to treat hypertension during pregnancy is Methyldopa (brand name Aldomet®), a molecule that belongs to adrenergic alpha-2 receptor agonists.

The correct answer is C.

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